Drug Reference
Tetrahydrozoline
Sympathomimetics, plain
OTC
Fact box
- Therapeutic class
- Sympathomimetics, plain
- Habit forming
- No
- Availability
- Over-the-counter (OTC)
Brand names
AltazineOptigeneVisine
Available as
0.5 MG/ML · Ophthalmic Solution2 MG/ML · Ophthalmic Solution3.5 MG/ML · Ophthalmic Solution0.5 MG/ML · Nasal Solution0.005 ML/ML · Ophthalmic Solution10 MG/ML · Ophthalmic Solution1 MG/ML · Ophthalmic Solution
FDA label sections are from openFDA and may not reflect the most recent labeling — confirm against the current DailyMed label.
Uses
Uses relieves redness of the eye due to minor eye irritations as a lubricant to prevent further irritation or to relieve dryness of the eye
How to use / dosing
Directions instill 1 to 2 drops in the affected eye(s) up to 4 times daily
Safety advice
Conservative summary derived from FDA labeling — defaults to “consult your doctor” unless the label is explicit. Not a substitute for your clinician’s advice.
PregnancyConsult your doctor
…or if the condition worsens or persists for more than 72 hours If pregnant or breast-feeding, ask a health professional before use.…
BreastfeedingConsult your doctor
…condition worsens or persists for more than 72 hours If pregnant or breast-feeding, ask a health professional before use.…
AlcoholNo information
No specific information in the FDA label.
DrivingNo information
No specific information in the FDA label.
KidneyNo information
No specific information in the FDA label.
LiverNo information
No specific information in the FDA label.
Warnings & precautions
Warnings For external use only Ask a doctor before use if you have narrow angle glaucoma When using this product pupils may become enlarged temporarily to avoid contamination, do not touch tip of container to any surface. Replace cap after using. if solution changes color or becomes cloudy, do not use overuse may produce increased redness of the eye remove contact lenses before using Stop use and ask a doctor if you experience eye pain changes in vision continued redness or irritation of the eye, or if the condition worsens or persists for more than 72 hours If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center (1-800-222-1222) right away.
Current FDA labels (DailyMed)
- VISINE RED EYE HYDRATING COMFORT EYE DROPS (TETRAHYDROZOLINE HYDROCHLORIDE AND POLYETHYLENE GLYCOL 400) SOLUTION/ DROPS [SAVINGS DISTRIBUTORS LLC]
- VISINE RED EYE TOTAL COMFORT MULTI-SYMPTOM (TETRAHYDROZOLINE HYDROCHLORIDE, POLYETHYLENE GLYCOL 400, AND ZINC SULFATE, UNSPECIFIED FORM) SOLUTION/ DROPS [KENVUE BRANDS LLC]
- VITAPHYTE REDNESS RELIEVER LUBRICANT EYE DROPS (REDNESS RELIEVER LUBRICANT EYE DROPS) SOLUTION [GUANGZHOU LIYAN COSMETICS TECHNOLOGY CO., LTD.]
- ROHTO ALL-IN-ONE (HYPROMELLOSE, TETRAHYDROZOLINE HYDROCHLORIDE, ZINC SULFATE) LIQUID [THE MENTHOLATUM COMPANY]
- ROHTO DIGI-EYE (HYPROMELLOSE, TETRAHYDROZOLINE HYDROCHLORIDE) LIQUID [THE MENTHOLATUM COMPANY]
Authoritative sources
Reference only — not clinical advice. Verify against current FDA labeling and consult a licensed provider. About half of pediatric drug use is off-label and is not reflected in FDA labels; absence of pediatric information does not mean a medicine is unused or unsafe in children.