Drug Reference

Pyrantel

Tetrahydropyrimidine derivatives

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OTC

Fact box

Therapeutic class
Tetrahydropyrimidine derivatives
Habit forming
No
Availability
Over-the-counter (OTC)

Brand names

AscarelDrontalDrontal PlusEquistrengthExodusGiarcidiaZap-WormerHeartgard PlusIverhartIverhart PlusLiqui-Vict 2XNemexNexGard PlusPyramaxRFDSentry HC Worm X DSSentry HC Worm X PlusSimparica TRIOStrongidSure Shot 2XTri-Heart PlusTriple WormerVirbantelWorm Protector 2X

Available as

0.136 MG · Chewable Tablet0.272 MG · Chewable Tablet0.068 MG · Chewable Tablet2.27 MG/ML · Oral Suspension0.15 MG/MG0.439 MG/MG144 MG/ML · Oral Suspension180 MG · Oral Tablet0.034 MG · Chewable Tablet0.24 MG · Chewable Tablet0.48 MG · Chewable Tablet0.06 MG · Chewable Tablet0.96 MG · Chewable Tablet0.12 MG · Chewable Tablet1.44 MG · Chewable Tablet150 MG · Chewable Tablet18.75 MG · Chewable Tablet37.5 MG · Chewable Tablet75 MG · Chewable Tablet9.375 MG · Chewable Tablet42.9 MG/ML · Oral Suspension50 MG/ML · Oral Suspension720.5 MG · Chewable Tablet4.54 MG/ML · Oral Suspension

FDA label sections are from openFDA and may not reflect the most recent labeling — confirm against the current DailyMed label.

Uses
Use For the treatment of pinworms.
How to use / dosing
Directions READ THE PACKAGE CAREFULLY BEFORE TAKING THIS MEDICATION. take only according to directions do not exceed the recommended dosage, unless directed by a doctor medication should only be taken one time as a single dose; do not repeat treatment when one individual in a household has pinworms, the entire household should be treated unless otherwise advised adults, children 12 years of age and over, and children 2 years to under 12 years of age: this product can be taken any time of day, with or without meals. It may be taken alone or with milk or fruit juice. use of a laxative is not necessary before, during, or after medication oral dosage is a single dose of 5 mg of pyrantel base per pound or 11 mg of pyrantel base per kilogram of body weight not to exceed 1 gram (1000mg) children under 25 lbs. or 2yrs old: do not use unless directed by a doctor Weight Dosage (taken as a single (1) dose as per weight) Less than 25 lb. or under 2 yrs. old do not use unless directed by a doctor 25-37 lbs. 2 tablets (125 mg) 38-62 lbs. 4 tablets (250 mg) 63-87 lbs. 6 tablets (375 mg) 88-112 lbs. 8 tablets (500 mg) 113-137 lbs. 10 tablets (625 mg) 138-162 lbs. 12 tablets (750 mg) 163-187 lbs. 14 tablets (875 mg) 188 lbs. and over 16 tablets (1,000 mg)

Safety advice

Conservative summary derived from FDA labeling — defaults to “consult your doctor” unless the label is explicit. Not a substitute for your clinician’s advice.

PregnancyCaution
…Warnings Ask a doctor before use if you have liver disease are pregnant Stop use and ask a doctor if any symptoms or pinworms are still present after treatment any worms other than pinworms are present before or after treatment any of these symptoms that…
BreastfeedingNo information
No specific information in the FDA label. Check LactMed →
AlcoholNo information
No specific information in the FDA label.
DrivingNo information
No specific information in the FDA label.
KidneyNo information
No specific information in the FDA label.
LiverCaution
…Warnings Ask a doctor before use if you have liver disease are pregnant Stop use and ask a doctor if any symptoms or pinworms are still present after treatment any worms other than pinworms are present before or after treatment any of these…
Warnings & precautions
Warnings Ask a doctor before use if you have liver disease are pregnant Stop use and ask a doctor if any symptoms or pinworms are still present after treatment any worms other than pinworms are present before or after treatment any of these symptoms that sometimes occur after taking the product persist: abdominal cramps nausea vomiting diarrhea headache dizziness Keep out of reach of children. In case of an accidental overdose get medical help or contact a Poison Control Center right away.
Current FDA labels (DailyMed)

86 marketed products on record (RxNorm)

Authoritative sources

Reference only — not clinical advice. Verify against current FDA labeling and consult a licensed provider. About half of pediatric drug use is off-label and is not reflected in FDA labels; absence of pediatric information does not mean a medicine is unused or unsafe in children.