Drug Reference
Potassium Phosphate
Rx only
Fact box
- Habit forming
- No
- Availability
- Prescription (Rx)
Brand names
Ionosol-MBIsolyte SIsolyte S in 5 % DextroseK-PhosK-Phos NeutralK-Phos No 2Phospha 250 NeutralTis-U-Sol
Available as
0.0408 MEQ/ML · Oral Solution5 ML · Injection15 ML · Injection50 ML · Injection155 MG · Oral Tablet236 MG/ML · Injectable Solution250 ML · Injection100 ML · Injection305 MG · Oral Tablet50 MG/ML · Injectable Solution0.00148 MEQ/ML · Injectable Solution0.2 MG/ML
FDA label sections are from openFDA and may not reflect the most recent labeling — confirm against the current DailyMed label.
Uses
INDICATONS AND USAGE For use in patients with elevated urinary pH. K-PHOS® ORIGINAL helps keep calcium soluble and reduces odor and rash caused by ammoniacal urine. Also, by acidifying the urine, it increases the antibacterial activity of methenamine mandelate and methenamine hippurate.
How it works
ACTIONS K-PHOS® ORIGINAL is a highly effective sodium-free urinary acidifier.
How to use / dosing
DOSAGE AND ADMINISTRATION Two tablets dissolved in 6-8 oz. of water 4 times daily with meals and at bedtime. For best results, let the tablets soak in water for 2 to 5 minutes, or more if necessary, and stir. If any tablet particles remain undissolved, they may be crushed and stirred vigorously to speed dissolution.
Side effects
ADVERSE REACTIONS Gastrointestinal upset (diarrhea, nausea, stomach pain, and vomiting) may occur with the use of potassium phosphate. Also, bone and joint pain (possible phosphate-induced osteomalacia) could occur. The following adverse effects may be observed with potassium administration: irregular heartbeat; dizziness; mental confusion; weakness or heaviness of legs; unusual tiredness; muscle cramps; numbness, tingling, pain, or weakness in hands or feet; numbness or tingling around lips; shortness of breath or troubled breathing.
Safety advice
Conservative summary derived from FDA labeling — defaults to “consult your doctor” unless the label is explicit. Not a substitute for your clinician’s advice.
PregnancyUnsafe
Pregnancy Teratogenic Effects Pregnancy Category C Animal reproduction studies have not been conducted with K-PHOS® ORIGINAL. It is also not known whether this product can cause fetal harm when administered to a pregnant woman or can affect reproductive capacity. This product should be given to a pregnant woman only if clearly needed.
BreastfeedingCaution
Nursing Mothers It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when this product is administered to a nursing woman.
AlcoholNo information
No specific information in the FDA label.
DrivingNo information
No specific information in the FDA label.
KidneyConsult your doctor
…with infected phosphate stones; in patients with severely impaired renal function (less than 30% of normal) and in the presence of hyperphosphatemia and…
LiverNo information
No specific information in the FDA label.
Contraindications
CONTRAINDICATIONS This product is contraindicated in patients with infected phosphate stones; in patients with severely impaired renal function (less than 30% of normal) and in the presence of hyperphosphatemia and hyperkalemia.
Interactions (label text — not an interaction checker)
Drug Interactions The use of antacids containing magnesium, calcium, or aluminum in conjunction with phosphate preparations may bind the phosphate and prevent its absorption. Potassium-containing medications or potassium-sparing diuretics may cause hyperkalemia when used concurrently with potassium salts. Patients should have serum potassium level determinations at periodic intervals. Concurrent use of salicylates may lead to increased serum salicylate levels since excretion of salicylates is reduced in acidified urine. Serum salicylate levels should be closely monitored to avoid toxicity.
Current FDA labels (DailyMed)
- THE CELL SALT CO. DAILY BLEND 12 IN 1 (CALC FLUOR, CALC PHOS, CALC SULPH, FERRUM PHOS, KALI MUR, KALI PHOS, KALI SULPH, MAG PHOS, NAT MUR, NAT PHOS, NAT SULPH, SILICEA) TABLET, SOLUBLE [THE CELL SALT COMPANY LLC]
- DEXTROSE AND ELECTROLYTE NO. 48 (SODIUM LACTATE, POTASSIUM CHLORIDE, MAGNESIUM CHLORIDE, MONOBASIC POTASSIUM PHOSPHATE, SODIUM CHLORIDE AND DEXTROSE MONOHYDRATE) INJECTION [BAXTER HEALTHCARE COMPANY]
- ESSENTIALS WHITEN AND STRENGTHEN (SODIUM FLUORIDE 0.24%) PASTE, DENTIFRICE [CHURCH & DWIGHT CO., INC.]
- EUTHYMOL WHITENING PURPLE CORRECTOR (SODIUM FLUORIDE) PASTE, DENTIFRICE [LG HOUSEHOLD & HEALTH CARE LTD.]
- IONOSOL MB AND DEXTROSE (DEXTROSE MONOHYDRATE, SODIUM LACTATE, POTASSIUM CHLORIDE, MAGNESIUM CHLORIDE, POTASSIUM PHOSPHATE, MONOBASIC, AND SODIUM PHOSPHATE, MONOBASIC, MONOHYDRATE) INJECTION, SOLUTION [ICU MEDICAL INC.]
Authoritative sources
Reference only — not clinical advice. Verify against current FDA labeling and consult a licensed provider. About half of pediatric drug use is off-label and is not reflected in FDA labels; absence of pediatric information does not mean a medicine is unused or unsafe in children.