Drug Reference

Loperamide / Simethicone

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Pediatric caution

Brand names

Imodium AdvancedImodium Multi-Symptom Relief

Available as

2 MG · Chewable Tablet2 MG · Oral Tablet
Multi-ingredient product
LoperamideSimethicone

This medicine contains more than one active ingredient. To avoid attributing one component’s information to the whole product, structured label sections aren’t shown here — see the component pediatric notes below and the full combination label on DailyMed.

Pediatric use

Pediatric caution

Not recommended in children <2 years; use with caution in older children due to risk of ileus and CNS effects.

Source: Loperamide labeling; AAP guidance.

⚑ About half of pediatric medication use is off-label and not described in FDA labels — absence of pediatric information does not mean a medicine is unused or unsafe in children. Confirm with your clinician.

Current FDA labels (DailyMed)

4 marketed products on record (RxNorm)

Reference only — not clinical advice. Verify against current FDA labeling and consult a licensed provider. About half of pediatric drug use is off-label and is not reflected in FDA labels; absence of pediatric information does not mean a medicine is unused or unsafe in children.