Drug Reference
Histamine
OTC
Fact box
- Habit forming
- No
- Availability
- Over-the-counter (OTC)
Brand names
ActivOn ArthritisAlo
Available as
0.25 MG/ML · Topical Cream0.28 MG/ML · Topical Cream1 MG/ML · Topical Cream0.5 MG/ML · Topical Cream1 MG/ML0.3 MG/ML · Topical Cream0.4 MG/ML · Topical Cream
FDA label sections are from openFDA and may not reflect the most recent labeling — confirm against the current DailyMed label.
Uses
Indications: For the temporary relief of minor aches and pains of muscles and joints, associated with arthritis, simple back aches, strains, bruises, and sprains.
How to use / dosing
Directions: Adults and children two-years of age or older: Apply to affected area not more than three to four times daily. Children under two-years of age: consult a physician.
Safety advice
Conservative summary derived from FDA labeling — defaults to “consult your doctor” unless the label is explicit. Not a substitute for your clinician’s advice.
PregnancyConsult your doctor
…If pregnant or breast feeding, contact a physician prior to use.
BreastfeedingNo information
No specific information in the FDA label. Check LactMed →
AlcoholNo information
No specific information in the FDA label.
DrivingNo information
No specific information in the FDA label.
KidneyNo information
No specific information in the FDA label.
LiverNo information
No specific information in the FDA label.
Warnings & precautions
Warnings: For external use only. Avoid contact with eyes. If symptoms persist for more than seven days, discontinue use and consult a physician. Keep out of reach of children. If swallowed, consult a physician ASAP. Do not apply to wounds or damaged skin. Do not bandage tightly. If pregnant or breast feeding, contact a physician prior to use.
Current FDA labels (DailyMed)
- ALLERGY CARE (ADRENALINUM, RAGWEED, POLLEN (AMBROSIA ARTEMISIAEFOLIA), APIS MELLIFICA, ECHINACEA (ANGUSTIFOLIA), HISTAMINUM HYDROCHLORICUM, LEDUM PALUSTRE, LYCOPODIUM CLAVATUM, NATRUM MURIATICUM, SULPHUR) LIQUID [NATURALCARE]
- S12 AIRBORNE (ALFALFA, ALLIUM SATIVUM, ARSENICUM IODATUM, BARLEY, BETULA PUBESCENS, BROWN RICE, CORN GRAIN, EUPHRASIA OFFICINALIS, FEATHER MIX, HAIR MIX, HISTAMINUM, HOUSE DUST MITE, LOLIUM PERENNE, OAT, PERFOLIATE HONEYSUCKLE, PHLEUM PRATENSE, POLLEN MIX, RYE, SABADILLA, SILICEA, SKIN MIX, SOLIDAGO VIRGAUREA, TARAXACUM OFFICINALE, TEREBINTHINA, WHEAT) SOLUTION/ DROPS [APEX ENERGETICS INC.]
- BITE CALM STINGS AND ITCHING (APIS MELLIFICA 9C, HISTAMINUM HYDROCHLORICUM 5C, LAPPA MAJOR 3C, URTICA URENS 5C) SPRAY [SEVENE USA]
- CLEAR SEASON SEASONAL AND RESPIRATORY ALLERGIES (ALLIUM CEPA 5C, EUPHRASIA OFFICINALIS 5C, HISTAMINUM HYDROCHLORICUM 5C, SABADILLA 5C) SPRAY [SEVENE USA]
- ALLER-CHORD A (ALFALFA, ALLIUM CEPA, AMBROSIA ARTEMISIAEFOLIA, BRYONIA (ALBA), CITRICUM ACIDUM, COUMARINUM, EUPHRASIA OFFICINALIS, GLANDULA SUPRARENALIS SUIS, HEPAR SUIS, HISTAMINUM HYDROCHLORICUM, HYDRASTIS CANADENSIS, JUNIPERUS COMMUNIS, MUCOSA NASALIS SUIS, NATRUM SULPHURICUM, PHOSPHORUS, POTHOS FOETIDUS, PULSATILLA (VULGARIS), SOLIDAGO VIRGAUREA, SULPHUR, TANACETUM VULGARE, TARAXACUM OFFICINALE, TRIFOLIUM PRATENSE) LIQUID [ENERGETIX CORPORATION]
Authoritative sources
Reference only — not clinical advice. Verify against current FDA labeling and consult a licensed provider. About half of pediatric drug use is off-label and is not reflected in FDA labels; absence of pediatric information does not mean a medicine is unused or unsafe in children.