Drug Reference
Dexchlorpheniramine
Substituted alkylamines
OTC
Fact box
- Therapeutic class
- Substituted alkylamines
- Habit forming
- No
- Availability
- Over-the-counter (OTC)
Brand names
Ryclora
Available as
2 MG · Oral Tablet0.2 MG/ML · Oral Solution2.5 MG/ML · Oral Solution6.25 MG/ML · Oral Solution5 MG/ML · Oral Solution1.8 MG/ML · Oral Solution0.4 MG/ML · Oral Solution0.6 MG/ML6 MG · Extended Release Oral Tablet6 MG · Oral Tablet
FDA label sections are from openFDA and may not reflect the most recent labeling — confirm against the current DailyMed label.
Uses
Uses ■ temporarily relieves these symptoms due to the common cold, hay fever (allergic rhinitis) or other upper respiratory allergies: ■ runny nose ■ sneezing ■ itching of the nose or throat ■ itchy, watery eyes ■ cough due to minor throat and bronchial irritation
How to use / dosing
Directions do not exceed recommended dosage. adults and children 12 years of age and over: 2 teaspoonfuls (10 mL) every 6 hours, not to exceed 8 teaspoonfuls (40 mL) in 24 hours. children 6 to under 12 years of age: 1 teaspoonful (5 mL) every 6 hours, not to exceed 4 teaspoonfuls (20 mL) in 24 hours. children under 6 years of age: consult a doctor.
Safety advice
Conservative summary derived from FDA labeling — defaults to “consult your doctor” unless the label is explicit. Not a substitute for your clinician’s advice.
PregnancyConsult your doctor
…■ new symptoms occur If pregnant or breast-feeding, ask a health professional before use.…
BreastfeedingConsult your doctor
…■ new symptoms occur If pregnant or breast-feeding, ask a health professional before use.…
AlcoholCaution
…may occur, especially in children ■ may cause marked drowsiness ■ alcohol, sedatives, and tranquilizers may increase the drowsiness effect ■ avoid alcoholic drinks ■ use caution when driving a motor vehicle or operating machinery Stop use and ask a doctor if ■…
DrivingCaution
…the drowsiness effect ■ avoid alcoholic drinks ■ use caution when driving a motor vehicle or operating machinery Stop use and ask a doctor if ■ cough persists for more than 1 week, tends to recur, or is accompanied by a fever, rash or persistent headache.…
KidneyNo information
No specific information in the FDA label.
LiverNo information
No specific information in the FDA label.
Warnings & precautions
Warnings Ask a doctor before use if you have ■ a cough that lasts or is chronic such as occurs with smoking, asthma, or emphysema ■ a cough that occurs with too much phlegm (mucus) ■ a breathing problem such as emphysema or chronic bronchitis ■ trouble urinating due to an enlarged prostate gland ■ glaucoma Ask a doctor or pharmacist before use if you are taking sedatives or tranquilizers When using this product ■ excitability may occur, especially in children ■ may cause marked drowsiness ■ alcohol, sedatives, and tranquilizers may increase the drowsiness effect ■ avoid alcoholic drinks ■ use caution when driving a motor vehicle or operating machinery Stop use and ask a doctor if ■ cough persists for more than 1 week, tends to recur, or is accompanied by a fever, rash or persistent headache. A persistent cough may be a sign of a serious condition. ■ new symptoms occur If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.
Current FDA labels (DailyMed)
- POLY-HIST DM (DEXCHLORPHENIRAMINE MALEATE AND DEXTROMETHORPHAN HBR) LIQUID [POLY PHARMACEUTICALS, INC.]
- VANACOF 2 (CHLOPHEDIANOL HCL, DEXCHLORPHENIRAMINE MALEATE) SOLUTION [GM PHARMACEUTICALS, INC]
- CORPHENA (DEXCHLORPHENIRAMINE MALEATE) SOLUTION [BLUCREST PHARMACEUTICALS LLC]
- VANACOF (CHLOPHEDIANOL HYDROCHLORIDE, DEXCHLORPHENIRAMINE MALEATE, AND PSEUDOEPHEDRINE HYDROCHLORIDE) LIQUID [GM PHARMACEUTICALS, INC]
- RYMED (DEXCHLORPHENIRAMINE MALEATE AND PHENYLEPHRINE HYDROCHLORIDE) TABLET, COATED [EDWARDS PHARMACEUTICALS, INC.]
Authoritative sources
Reference only — not clinical advice. Verify against current FDA labeling and consult a licensed provider. About half of pediatric drug use is off-label and is not reflected in FDA labels; absence of pediatric information does not mean a medicine is unused or unsafe in children.