Drug Reference
Brimonidine
Other dermatologicals
OTC
Fact box
- Therapeutic class
- Other dermatologicals
- Action class
- alpha-Adrenergic Agonist
- Mechanism
- Adrenergic alpha-Agonists
- Habit forming
- No
- Availability
- Over-the-counter (OTC)
Brand names
AlphaganCombiganLumifyMirvasoSimbrinzaYuvezzi
Available as
2 MG/ML · Ophthalmic Suspension0.0033 MG/MG · Topical Gel0.25 MG/ML · Ophthalmic Solution1 MG/ML · Ophthalmic Solution2 MG/ML · Ophthalmic Solution1.5 MG/ML · Ophthalmic Solution
FDA label sections are from openFDA and may not reflect the most recent labeling — confirm against the current DailyMed label.
Uses
Use relieves redness of the eye due to minor eye irritations
How to use / dosing
Directions adults and children 5 years of age and over: instill 1 drop in the affected eye(s) every 6-8 hours do not use more than 4 times daily remove contact lenses before use wait at least 10 minutes before re-inserting contact lenses after use if using other ophthalmic products while using this product, wait at least 5 minutes between each product to avoid contamination, do not touch tip of container to any surface replace cap after each use children under 5 years of age: consult a doctor
Safety advice
Conservative summary derived from FDA labeling — defaults to “consult your doctor” unless the label is explicit. Not a substitute for your clinician’s advice.
PregnancyConsult your doctor
…of the eye condition worsens or persists for more than 3 days If pregnant or breast-feeding, ask a health professional before use.…
BreastfeedingConsult your doctor
…condition worsens or persists for more than 3 days If pregnant or breast-feeding, ask a health professional before use.…
AlcoholNo information
No specific information in the FDA label.
DrivingNo information
No specific information in the FDA label.
KidneyNo information
No specific information in the FDA label.
LiverNo information
No specific information in the FDA label.
Warnings & precautions
Warnings For external use only Do not use if solution changes color or becomes cloudy Stop use and ask a doctor if you experience eye pain, changes in vision, continued redness or irritation of the eye condition worsens or persists for more than 3 days If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.
Current FDA labels (DailyMed)
- BRIMONIDINE TARTRATE SOLUTION/ DROPS [MICRO LABS LIMITED]
- BRIMONIDINE TARTRATE AND TIMOLOL MALEATE OPHTHALMIC SOLUTION (BRIMONIDINE TARTRATE AND TIMOLOL MALEATE) SOLUTION/ DROPS [GLAND PHARMA LIMITED]
- BRIMONIDINE TARTRATE AND TIMOLOL MALEATE SOLUTION/ DROPS [UPSHER-SMITH LABORATORIES, LLC]
- BRIMONIDINE TARTRATE OPHTHALMIC SOLUTION SOLUTION/ DROPS [LIFESTAR PHARMA LLC]
- BRIMONIDINE TARTRATE AND TIMOLOL MALEATE SOLUTION/ DROPS [SANDOZ INC]
Authoritative sources
Reference only — not clinical advice. Verify against current FDA labeling and consult a licensed provider. About half of pediatric drug use is off-label and is not reflected in FDA labels; absence of pediatric information does not mean a medicine is unused or unsafe in children.